In a futuristic era plagued by Earth's overpopulation crisis, humanity turns to Mars for salvation after centuries of terraforming efforts. However, the colonization of Mars triggers an unimaginable horror when mutated cockroaches evolve into monstrous humanoids with a deadly agenda. As a second expedition sets foot on the Red Planet to confront this threat, they realize that the Bugs Procedure they underwent has transformed them into something beyond human, setting the stage for a harrowing battle for survival.