Nichijou follows the everyday escapades of three close high school friends - Mio Naganohara, Yuuko Aioi, and Mai Minakami. Their mundane routines take a whimsical turn when they cross paths with the brilliant Hakase Shinonome, her robot companion Nano, and the articulate cat Sakamoto. Amidst the ordinary activities like strolling to school, encountering a chatty crow, socializing with pals, and witnessing the principal perform wrestling moves on a deer, these six individuals navigate a blend of normalcy and the downright bizarre in their lives and those of the people around them.