Joe Higan, a renegade ninja seeking solace in rural America with his loved ones, is thrust back into his dark past when his former clan's assassins mercilessly attack, leaving him for dead. Reborn as Ninja Kamui, he embarks on a vengeful journey to confront his betrayers. In a clash of tradition and modernity, Kamui, a 21st-century ninja, skillfully combats advanced weaponry with his ancient techniques. His path is fraught with deadly adversaries like trained killers, cybernetic soldiers, and rival ninjas, all leading to a final showdown against the very organization that shaped his destiny.