Phantasy Star Online 2 The Animation follows Itsuki Tachibana, a high school student who stands out by not participating in the latest gaming craze like his peers. Despite this, Itsuki excels in academics and is always available to help with various club activities, making him a versatile asset. His competence catches the eye of the student council president, Rina Izumi, a paragon of perfection in looks, popularity, athleticism, and grades. Rina enlists Itsuki as the student council's vice president to investigate the impact of the MMO game Phantasy Star Online 2 on the student body's social dynamics. As Itsuki delves into this new venture, will he adapt to the gaming world and uncover the true influence of the game on his peers?