Years after the Order of the Sword turmoil, Kyrie and Nero reside together when they encounter the brash weapon artisan, Nico. Despite Nico's initial abrasiveness, Nero starts to bond with her. Soon after, a demon targets Nero, prompting Dante's ally Morrison to introduce him to enigmatic V, who unveils a mission. V reveals to Dante that quelling this demon embodies his purpose in battle. This precursor tale to Devil May Cry 5 delves into Nero's arm loss and Dante and V's journey to Red Grave City.