Identifying as ES, Ryousuke Akiba carries the legacy of a cryptic scientific project, granting him longevity beyond two centuries and extraordinary psychic abilities. With the power to delve into minds, unveil hidden truths, and manipulate memories to forge intimate connections with strangers, Ryousuke navigates the streets of Tokyo in a quest shrouded in mystery. Unseen and enigmatic, his existence remains a puzzle until Dr. Mine Kujyou, a resolute scientist, encounters a being defying all conventional understanding of genetic science–ES, harbinger of the immortal Eternal Sabbath gene. Yet, as revelations unfold, the question lingers: Are there others like him?