During a school trip, Fudou Jun, a teacher, finds herself and her students targeted by a group of martial artists who are revealed to be demons in disguise. Tragedy strikes as Jun is assaulted and transforms into Devilman Lady, a powerful being. With her new abilities, she defeats the demons and safeguards the students. As Jun grapples with her transformation, the implications of her hybrid nature on both herself and humanity loom large, raising questions about the unknown dangers lurking in the world.