In Academy City, where most of the population are students with unique powers ranked from Level 0 to 5, Touma Kamijou stands out as a powerless Level 0 esper. Despite his seemingly useless ability, his right hand possesses the extraordinary power to negate any supernatural phenomena it touches, earning the name 'Imagine Breaker.' Constantly plagued by misfortune, Touma's life takes a drastic turn when a girl named Index Librorum Prohibitorum crashes into his life, seeking refuge from magicians hunting her. As Touma delves into a realm of magic previously unknown to him, he embarks on a journey to navigate the complexities of both the scientific and magical worlds. How will this ordinary boy confront the challenges that await him in this extraordinary new reality?