In Bokusatsu Tenshi Dokuro-chan, Sakura Kusakabe, a 13-year-old student, inadvertently triggers a bizarre scenario where women cease aging after twelve due to his ill-conceived plan for a 'Pedophile's World.' This angers God, resulting in immortality for all. Dokuro Mitsukai, an angelic assassin, is sent back from the future to eliminate Sakura, but instead opts to prevent his research on immortality. Despite Dokuro's efforts, her impulsive actions with her powerful weapon, Excaliborg, frequently lead to Sakura's demise, only to revive him instantly. Sabato, another assassin from the same angelic order, employs seduction in her mission to fulfill Sakura's assassination.