The story revolves around Masamune Izumi, a light novel author in high school. Masamune's little sister is Sagiri, a shut-in girl who hasn't left her room for an entire year. She even forces her brother to make and bring her meals when she stomps the floor. Masamune wants his sister to leave her room, because the two of them are each other's only family. Masamune's novel illustrator, penname “Ero Manga Sensei,” draws extremely perverted drawings, and is very reliable. Masamune had never met his illustrator, and figured he was just a disgusting, perverted otaku. However, the truth is revealed … that his “Ero Manga Sensei” is his own younger sister! To add to the chaos that erupts between the siblings, a beautiful, female, best-selling shoujo manga creator becomes their rival!