Following the serialization of their latest manga, 'Detective Trap,' the duo Akito Takagi and Moritaka Mashiro, known as Muto Ashirogi, edge closer to achieving fame as mangaka. While Mashiro sees serialization as a stepping stone, aiming to fulfill a promise of marrying his childhood sweetheart and aspiring voice actress, Azuki Miho, once their manga receives an anime adaptation, the duo must work diligently to elevate Ashirogi's popularity. Amid a competitive landscape populated by talented mangaka like the eccentric Eiji Niizuma, the poised Yuriko Aoki and her mentor Takurou Nakai, the lethargic Kazuya Hiramaru, and the confrontational Shinta Fukuda, Muto Ashirogi faces both camaraderie and rivalry on the path to crafting a blockbuster. Balancing the demands of a new, untested editor, the pair strives to retain their serialization, dominate Shounen Jack's rankings, and realize their dream of an anime adaptation. With fresh alliances and competitions, Bakuman. 2nd Season chronicles Takagi and Mashiro's journey of dedication, ambition, and youthful romance.