Sakamachi Kinjirou suffers from a severe fear of women due to his female wrestler upbringing, causing nosebleeds at the slightest touch. His world turns chaotic when he learns Subaru-sama, the suave bodyguard, is actually a girl. To keep this secret, Kanade offers to help him conquer his phobia. Amidst a cross-dressing butler, a twisted beauty, a BL writer, a pro-wrestler hopeful, and a ghost cohabitant, Kinjirou's high school life becomes a whirlwind of eccentric escapades in Mayo Chiki!.