Ryo Saeba, the renowned 'City Hunter,' partners with Kaori to tackle various cases. Their latest involves protecting a model named Ai Shindo who was assaulted. Unexpectedly, Kaori's old friend, Shinji Mikuni, enters the scene as the CEO of an IT firm employing Ai. As tensions rise in Shinjuku with mercenaries amassing and a notorious arms dealer introducing a deadly weapon in Japan, Ryo and Kaori find their bond tested by Mikuni's presence.