In the desolate district known as Hole, where chaos reigns and the powerful prey on the weak, magic users test their abilities without restraint. Viewed as superior beings, they show no mercy to the residents of Hole, using them for experiments and disposing of them callously. Amid this lawless realm, Kaiman, a man with a reptilian appearance and immunity to magic, seeks vengeance against these tyrannical sorcerers. With his loyal bayonets and the support of Nikaidou, who runs the Hungry Bug restaurant, Kaiman embarks on a relentless quest for answers and normalcy. Dorohedoro unfolds in a darkly imaginative world where humor blends with brutality, offering a twisted narrative that delves into the lives of Hole's inhabitants. Through its grim yet captivating storytelling, the series unveils a realm of eerie origins and unsettling beauty, not suited for the faint of heart.