In a post-war Japan saved by the SHELL system, offering eternal health through nanotechnology, society demands 19-hour workdays in exchange. Those who disconnect face a rare transformation into monstrous Lost beings. Amidst rising social unrest, factory worker Takeichi and artist Youzou rebel against their fate but end up turned Lost. A unique ability in Youzou sparks hope for humanity's revival, as he and investigator Yoshiko delve into the surge of Human Lost incidents, crucial for civilization's survival.