In a world where suffering lurks within hearts, a peculiar affliction known as the 'mystery disease' emerges, triggered by inexplicable thoughts. Amidst this enigma, a doctor named Ramune and his apprentice confront this elusive illness that defies conventional medical treatment. Renowned for his unorthodox methods and brash demeanor, Ramune, despite his unconventional appearance, possesses an uncanny ability to unravel the emotional turmoil underlying his patients' maladies. As they delve into the hidden truths behind each case, a deeper mystery unfolds, transcending mere physical ailments.