Accompanied by his loyal comrades Cho Hakkai, Sha Gojyo, and Son Goku, Priest Genjo Sanzo embarks on a perilous quest to thwart the revival of the malevolent demon Gyoumao. Along the way, the notorious Sanzo Ikkou face relentless attacks from demon assassins, all while grappling with internal conflicts that threaten their unity as they confront a formidable adversary.