After a global upheaval caused by a small percentage of the population gaining psychokinetic powers, a fragile peace is maintained through strict societal regulations. In the town of Kamisu 66, Saki Watanabe, alongside her friends at Sage Academy, explores their newly discovered abilities. As they delve into mysteries like the enigmatic Tainted Cats and those without powers, they uncover unsettling truths about their world. Shinsekai yori follows Saki and her companions on a tumultuous journey of self-discovery within a seemingly perfect society, where confronting the harsh realities of their existence becomes inevitable.