In a post-apocalyptic America plagued by D2 creatures with a loathing for music, citizens are forbidden from playing melodies to avert disaster. Takt Asahina, a gifted pianist, becomes a Conductor after a D2 attack, linking him to Destiny, a Musicart, and entwining his fate with Anna, who seeks justice for her sister's death. Together, they venture towards Symphonica Headquarters in New York, facing perilous challenges. While Takt yearns to play the piano again, drawing D2s near, Destiny's commitment leads them into jeopardy. Can they navigate the D2-infested path and overcome the trials en route to New York City?