Tsunayoshi Sawada, a bumbling and infatuated middle schooler known as 'Loser Tsuna,' finds his mundane existence upended by Reborn, a baby hitman from Italy sent to groom him as the next boss of the Vongola Mafia family. With the aid of his unorthodox mentor and newfound mafia connections, Tsuna embarks on a challenging journey from mediocrity to potentially ruling a notorious crime syndicate.