Yukinari, a boy who is often mistreated due to his small stature, experiences an unusual condition where he breaks out in hives whenever girls touch him. His life takes a fantastical turn when he is unexpectedly whisked away to Seiren, a city in a mystical world revolving around Earth, predominantly inhabited by women. Amidst this strange setting, Yukinari finds solace in his unaffected friendship with Miharu-chan.