Kujo Jotaro, a typical high-schooler in Japan, finds himself believing he's possessed by a spirit, leading him to confine himself in a prison. Through encounters with his grandfather Joseph Joestar and battles with Joseph's comrade Muhammad Abdul, Jotaro discovers that this 'Spirit' is actually Star Platinum, his Stand—a manifestation of his fighting prowess. As his mother falls ill after acquiring a Stand, Jotaro uncovers the truth: the malevolent vampire Dio Brando has resurfaced a century after his initial defeat by Jonathan Joestar, Jotaro's ancestor. Determined to vanquish Dio once and for all, Jotaro embarks on a journey to Egypt alongside Joseph and Abdul.