Embarking on her high school journey, Chiyo Mihama stands out as a unique freshman—a small, 10-year-old genius who adores plush toys and cooking from scratch. Surrounded by a cast of eccentric classmates in Yukari Tanizaki's homeroom, where oddities abound, Chiyo finds company in the lively but scatterbrained Tomo Takino, the short-tempered Koyomi Mizuhara, the enigmatic cat-loving Sakaki, and the dreamy transfer student Ayumu Kasuga. Together, this endearing group navigates the highs and lows of school life, sharing in laughter, surreal escapades, and poignant reflections on the fleeting, emotional tapestry of adolescence.