In an alternate version of Japan's Meiji Era, humans and spirits coexist amid rising Western influence. Conflicts arise as Western faiths challenge traditional beliefs. The Ministry of Spirits forms, pairing male soldiers with female youkai to ease tensions. However, soldier Kei Agemaki fears youkai, and spirit Zakuro detests humans embracing Western customs. Forced to collaborate, their lives take a thrilling turn as they navigate this unlikely partnership.