In a tale of two Nanas, we meet Nana Komatsu, a lovestruck and dependent 20-year-old yearning to break free from her small town life by following her boyfriend to Tokyo. In contrast, Nana Osaki, a fierce punk rock singer, sets her sights on a music career in the city. By chance, these two strangers, both named Nana, cross paths on a train to Tokyo, leading to a shared apartment and a deepening friendship. Together, they navigate through love, music, and hardships, testing the strength of their inseparable bond.